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11 Mar, 26
New guidelines on pulmonary embolism (PE) offer evidence based recommendations for evaluating, managing, and following up adults with acute PE. Endorsed by eight societies, it stresses multidisciplinary care across emergency, inpatient, & outpatient settings.
26 Feb, 26
ADA 2026 outlines the standards for obesity pharmacotherapy. It recommends combining person-centered medication with lifestyle changes for adults with obesity. It details weight-loss targets and drug benefits for comorbidities
24 Mar, 26
Diabetes Obes Metab.
- Kailuan cohort (n=60,402, AF-free) tracked BMI, weight, & waist circumference over 4 years, across 13 yrs median follow-up, 582 AF cases emerged
- In men, BMI reduction >2.5 kg/m² (HR 0.663), weight reduction >5 kg (HR 0.662), WC reduction >4 cm (HR 0.768) reduced AF risk; in women, WC reduction>4 cm (HR 0.499) was protective
- Similar patterns were seen in overweight/obese, sustained weight loss lowered AF incidence.
23 Mar, 26J Neurol.
- The PEDIGREE (Pediatric Italian Genetic and Environment Exposure) study found a significant association between pediatric multiple sclerosis (MS) and higher ozone exposure
- Exposure to O₃ levels during the first (OR 1.11; p=0.007), second (OR 1.10; p=0.012), and third (OR 1.09; p=0.025) year before onset increased pediatric MS risk by about 10% per unit rise, independent of demographic and environmental confounders.
17 Mar, 26J Diabetes Sci Techn...
- The meta analysis of 16 studies (10 quantitative; n=1657) compared the CGM-derived metrics between prediabetics & normoglycemics
- Prediabetes was consistently linked to higher CGM metrics vs. normoglycemia: MAGE (MD 9.41 mg/dL), TAR% (MD 5.68%), & 24 h mean glucose (MD 7.91 mg/dL)
- This first quantitative evidence suggests that CGM discriminates prediabetes & normoglycemia, & can support refined risk assessment.
17 Mar, 26J Glaucoma.
- In a TriNetX cohort (T1DM: N = 166,471; T2DM: N = 5,745,652), diabetic retinopathy (DR) was linked to higher risk of ocular hypertension (OHT)/ primary open angle glaucoma (POAG)
- T1DM with DR had 4.966-fold OHT risk & 4.262-fold POAG risk T2DM with DR showed 2.651-fold OHT risk & 2.62-fold POAG risk
- Risk was greater in PDR vs. NPDR, findings underscore vigilant screening & comprehensive management.
2 Mar, 26
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