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14 Aug, 26
Obesity is a chronic, complex disease. Guidelines from the ADA’s Obesity Association, recommend annual screening with BMI, ethnicity-specific diagnostic criteria, waist circumference assessment, & comprehensive staging to guide personalized care.
14 Aug, 26
The ESPID Clinical Practice Guidelines recommend penicillins as first-line treatment for pediatric Group A Streptococcal (iGAS) infections, with the addition of clindamycin for toxin-mediated cases.
24 Aug, 26
Pediatr Infect Dis J
- Among 3,780 infants ≤90 days, Respiratory Syncytial Virus (RSV) was the most frequently detected respiratory virus
- Invasive bacterial infection (IBI) risk was lower in febrile infants with a respiratory virus than without viral detection (1.3% vs 4.9%; P<0.001)
- No IBIs occurred with RSV (n=259), influenza virus (n=67), parainfluenza virus (n=66), human metapneumovirus (hMPV; n=13), or adenovirus (n=11) alone.
24 Aug, 26
A case series of patients with absolute insulin deficiency and poor glycemic control despite insulin therapy. Could sitagliptin offer an adjunctive approach in this challenging setting? Click here to read the treatment.
21 Aug, 26Diabetes Metab Syndr...
- Analysis of more than 56000 health records across India showed a concurrent hypertension-diabetes prevalence of ~5%, nearly 2-fold higher than expected by chance, indicating significant synergy
- Synergy intensified from ~40 yrs, rose until ~58 yrs & plateaued at ~17% by ~70 yrs
- Hypertension was ~4× more common in diabetics & diabetes, ~2.5× more common in hypertensives, supporting integrated screening from age 40.
18 Aug, 26Diabetes Obes Metab.
- Among 64,404 patients with T2DM, use of SGLT-2 inhibitors, DPP-4 inhibitors, or thiazolidinediones as second-line therapy after metformin was associated with a significantly lower risk of insulin initiation vs insulin secretagogues (HR 0.62, 0.75, and 0.59, respectively)
- Over 2.9 years, SGLT-2 inhibitors also showed greater treatment durability, supporting their use to delay insulin dependence.
20 Aug, 26
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