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24 Jun, 26
ECO 2026
Key sessions presented presented at 33rd European Congress on Obesity held at Istanbul, Türkey.
24 Jun, 26ECO 2026
Key sessions presented presented at 33rd European Congress on Obesity held at Istanbul, Türkey.
26 Jun, 26Indian J Pediatr.
- Next-generation sequencing (NGS) expands diagnostic scope for rare genetic disorders.
- Early use in diagnostic pathway improves cost-effectiveness vs prolonged workup.
- Challenges: genomic literacy, lab capacity, workforce, variant interpretation.
- Requires expertise in pre/post-test genetic counseling for optimal clinical utility.
26 Jun, 26Front. Nutr.
- Repeated low serum Mg (<1.7 mg/dL) in ≥50 yrs linked to increased incident all-cause dementia vs normal Mg.
- Strongest risk seen for vascular dementia (HR 1.63), suggesting cerebrovascular mediation.
- Associations also observed with stroke (HR 1.37) and all-cause mortality (HR 1.52).
- High Mg associated with increased dementia risk (HR 1.25); highlights importance of Mg homeostasis.
25 Jun, 26Int. J. Infect. Dis.
- Antibiotics for uncomplicated sore throat prevent few invasive Group A Streptococcus (iGAS) cases (≤6.7% children, ≤2.8% adults).
- Targeted strategy prevents even fewer cases (≤1.6% children, ≤1.2% adults).
- Very high number needed to treat (NNT)(12,000–110,000) and swabs needed (45,000–110,000) to prevent one iGAS case.
- Routine antibiotic use not justified due to minimal benefit, adverse effects, and increased w...
25 Jun, 26Cardiovasc Diabetol.
- TyG-KDM-BA index, integrating metabolic dysfunction (TyG index) & biological aging (KDM-BA), predicted CVD risk in CKM stages 0–3
- Each 1 SD rise in TyG-KDM-BA was linked to higher risk of CVD in UKB cohort (HR per 1-SD=1.65) & CHARLS cohort (HR=1.25)
- Higher quartiles showed elevated risk (UKB HR=3.97; CHARLS HR=1.92)
- AUC 0.657–0.659 indicated superior discrimination vs conventional indices, validated externally.
25 Jun, 26
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